Ing Thiazide metung yang kataya nung nu iti dati yang magagamit keng metung a tinduk a molecule[1] ampon pinduan a diuretic.[2]

Chlorothiazide
Hydrochlorothiazide
Bendroflumethiazide

Dening kayanib keng pinduan a diuretic ilapin deng manibatan keng benzothiadiazine. Kalasag nala deng Na+/Cl- paramasipsip pasibayu ibat keng distal convoluted tubule keng batu kapamilatan ning pamanyabat kareng thiazide-mapamakiramdam Na+-Cl- symporter. Deng Thiazides maging lang sangkan keng pangawala ning potassium ampong pangarakal ning serum uric acid. Ing balangkas pangchemica ning minunang thiazide diuretics atin yang palsingsing ing thiazide ; ing kataya magagamit ya naman kareng panulung a milulupa bisa na enaman chemically thiazides, kalupa na mo deng chlortalidone ampong metolazone, maigpit deni mayayaus lang balumu thiazide-a diuretics, dapot keraklan ing thiazide magagamit ya mu agiang makananu.

Dalerayan

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Moreno, E (2006). Affinity-defining Domains in the Na-Cl Cotransporter. J. Biol. Chem. 281, 17266-17275.

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Suglung Palual

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